Pain & Mobility

Nerve Pain

Supplements and products for nerve discomfort, tingling and numbness. Neuropathy has many causes, so the first step is always finding the reason.

What we cover

  • Alpha-lipoic acid and B vitamins
  • Topical products such as capsaicin
  • Neuropathy in diabetes
  • Foot care and safety

Common ingredients and the evidence

Ingredient or optionUsed forEvidenceNotes
Vitamin B12Nerve symptoms from deficiencyModerateEffective if you're deficient, common with metformin.
Topical capsaicinNerve painModerateCan burn at first.
Alpha-lipoic acidDiabetic neuropathy symptomsLimitedModest effects in some trials.
Acetyl-L-carnitineNerve painLimitedSmall studies.

Ratings follow our evidence scale and are updated as new research appears.

Claims to be careful with. No supplement can "regenerate" nerves or cure neuropathy. Be wary of products promising to end nerve pain permanently.

See a doctor if…

You have new numbness, tingling, burning or weakness, especially in your feet. If you have diabetes, check your feet daily and report any sores.

Medical disclaimer →

These statements have not been evaluated by the Food and Drug Administration. Products discussed are not intended to diagnose, treat, cure, or prevent any disease.